What causes high mean platelet volume?
High mpv is connected to various conditions, such as obesity, metabolic syndrome, type 2 diabetes, coronary artery disease, and inflammation. MPV is also linked to the development of chronic kidney disease. If you are a smoker, you have higher MPV levels.
What causes high MPV?
Mean platelet volume ( mpv is a measure of the average size of platelets in the blood. People with high MPV have larger platelets than people with lower levels. While tests for high MPV can be performed in a doctor’s office, there is no specific cause for the condition.
What is the cause of high MPV?
The exact cause of high MPV is unknown. But several studies have linked the presence of a specific DNA sequence in the MPV gene with high MPV. This gene is called the platelet glycoprotein (GP) receptor. People who have this specific type of MPV have more receptors on their platelets than people without this type. This means that they have a greater chance of forming clots, which can lead to complications such as heart attacks and stroke.
What does high mean platelet volume mean?
An increased MPV is often associated with a hypercoagulable state, including coronary artery disease, stroke, and venous thromboembolism. People with a higher MPV have a higher risk of developing these conditions. Other disorders that can lead to an increased MPV are hypertension, diabetes, thyroid disease, obesity, obstructive sleep apnea, and nonalcoholic fatty liver disease.
What does high MPV mean?
The mean platelet volume is a measure of the average size of platelets in the blood. MPV is usually less than or equal to 7.5, and both higher and lower values are associated with increased risk for developing cardiovascular disease and other conditions. For example, high MPV has been linked to coronary artery disease, increased risk of thrombosis and greater sensitivity to aspirin.