What does high mean platelet volume indicate?
High platelet volume ( hpv refers to having an increased amount of circulating platelets. Researchers have found that developing thrombotic disease is correlated with an increase in platelet count and volume. Those with a higher platelet count are at a greater risk for future heart attacks, stroke, and other thrombotic diseases. Doctors sometimes check a patient's platelet count for signs of increased risk of developing thrombotic disease.
What does high MPV mean in a woman?
You may have heard that high MPV is linked to increased risk for severe forms of coronary artery disease and thrombosis, or blood clots, in women. Large platelets are more active and can form clots more quickly, which can lead to increased risk for heart attack and stroke. However, high MPV is not an independent risk factor for coronary artery disease or thrombosis in women.
What does high mean for platelet volume?
Platelet volume is the measurement of the total volume of platelet cells within a single sample of blood. Due to its association with coronary artery disease, mean platelet volume (MPV) is often used to assess risk. MPV is routinely evaluated in those with coronary artery disease or other thrombotic disorders because of its association with increased thrombotic activity.
What does high mean for platelet size?
The size of platelets determines their function. Smaller platelets are more active and respond faster to damage than larger platelets. Thus, people who have higher platelet counts may be more prone to developing more serious conditions. Not only do large platelets take up more space in the blood, they are more likely to form clots in the coronary arteries. This is why thrombocytosis is considered a risk factor for coronary artery disease.
What does high MPV mean?
High platelet count is not a disease in itself. However, it is sometimes a sign of an underlying health condition. There are several conditions that can cause high MPV, including atherosclerosis, inflammation, and different types of cancer. Other conditions that can increase the risk of developing thrombosis and coronary heart disease have also been found to be associated with high MPV, such as Alzheimer’s disease, insulin resistance, metabolic syndrome, and obstructive sleep apnea.