Where does substrate level phosphorylation take place?
The starting point of substrate level phosphorylation is the ADP/ATP carrier on the inner mitochondrial membrane. ADP that is produced by the oxidative phosphorylation of nutrients is transported into the matrix to fuel respiration. In the matrix ADP is converted to ATP by oxidative phosphorylation. In order to accept ADP as a substrate, the ADP/ATP carrier can be in either an ADP-bound or an ATP-bound form. In the ADP-bound
What type of substrate level phosphorylation take place?
In the Class C cytochrome P450 (CYP) pathway, three different types of substrate level phosphorylation (SLP) take place: flavin-dependent, NADPH-dependent, and metal-dependent. The flavin-dependent SLP involves the flavin cofactor that is bound to the CYPs. This reaction is dependent on the CYPs using solar energy to reduce the flavin cofactor. NADPH-dependent SLP is dependent on having a reduced form of
What are substrate level phosphorylation?
In substrate level phosphorylation, the energy of ATP hydrolysis is used to directly phosphorylate a substrate. This means that the energy generated during the breakdown of one molecule of ATP is used to phosphorylate one substrate.
Where does substrate level phosphorylation take place in the body?
Protein level phosphorylation is important for the functioning of all living cells. It is required for cell growth and division, the cell cycle, and the function of the body. Protein level phosphorylation also plays a key role in the development of the nervous system as well as the regulation of cell metabolism.
Where is substrate level phosphorylation taking place?
In plants and algae, there are two possible locations where substrate level phosphorylation can occur: in the chloroplast or in the cytosol. In the chloroplasts, light-driven reactions occur. When stromal proteins are enzymatically transferred into the thylakoid membranes of chloroplasts, ADP is added. This results in a high energy charge which can be used to power the production of ATP by the chloroplasts. In the cyt